Description

Ethyl 1-(Pyridin-4-Yl)Cyclopropanecarboxylate is a high-value, nitrogen-containing heterocyclic building block featuring a cyclopropane ring fused with a pyridine moiety. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique bicyclic structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced organic materials and functional polymers requiring specific nitrogen-containing heterocycles.
• Chemical Biology Probes: Utilized as a core scaffold for developing molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	Ethyl 1-(Pyridin-4-Yl)Cyclopropanecarboxylate
CAS No.	858035-95-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	1-(4-Pyridyl)cyclopropanecarboxylic acid ethyl ester; Ethyl 1-(4-pyridinyl)cyclopropanecarboxylate; 1-Pyridin-4-ylcyclopropanecarboxylic acid ethyl ester; 4-Pyridinecyclopropanecarboxylic acid ethyl ester; 858035-95-7; Ethyl 1-(4-Pyridyl)cyclopropanecarboxylate; 1-(Pyridin-4-yl)cyclopropanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-(Pyridin-4-Yl)Cyclopropanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.