Description

2-Bromo-5-Isopropoxypyridine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and an isopropoxy group, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Used to create tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Bromo-5-Isopropoxypyridine
CAS No.	857992-23-5
Molecular Formula	C8H10BrNO
Molecular Weight	216.08 g/mol
Synonyms	5-Isopropoxy-2-bromopyridine; 2-Bromo-5-(1-methylethoxy)pyridine; 2-Bromo-5-(propan-2-yloxy)pyridine; Pyridine, 2-bromo-5-(1-methylethoxy)-; 2-Bromopyridin-5-yl isopropyl ether; Isopropyl 2-bromopyridin-5-yl ether
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Isopropoxypyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.