Description

1'-Benzyl-2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] is a high-value, complex spirocyclic organic compound that serves as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique molecular architecture, featuring fused isoquinoline and piperidine rings, makes it a versatile building block for constructing novel bioactive molecules. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential drug candidates targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Utilized as a core scaffold for developing molecular probes to study biological pathways and protein function.
• Academic Research: Used in universities and research institutes for investigations into new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1'-Benzyl-2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine]
CAS No.	857898-64-7
Molecular Formula	C20H22N2
Molecular Weight	290.41 g/mol
Synonyms	1'-Benzyl-1'H-spiro[piperidine-4,4'-isoquinoline]; 1'H-Spiro[piperidine-4,4'-isoquinoline], 1'-benzyl-; 1'-Benzylspiro[piperidine-4,4'-isoquinoline]; Spiro[piperidine-4,4'-isoquinoline], 1'-benzyl-; Benzylspiro[piperidine-4,4'-isoquinoline]; 857898-64-7; 1'-Benzyl-2,3-dihydrospiro[isoquinoline-4,4'-piperidine]; 1'-Benzyl-1'H-spiro[piperidine-4,4'-isoquinoline]
EINECS	Contact for details

Quality Control

Our 1'-Benzyl-2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch and supplied upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.