Description

6-Chloro-1-(p-Tolylsulfonyl)-2,3-Dihydroquinolin-4-One is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of novel pharmacologically active molecules, particularly within heterocyclic chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex chemical libraries.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel quinoline-based drug candidates with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of targeted compound libraries.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex molecular architectures, leveraging its reactive chloro and sulfonyl groups.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents and pesticides.
• Material Science Exploration: May be utilized in the research and development of specialty chemicals and advanced organic materials.

Basic Information

Product Name	6-Chloro-1-(p-Tolylsulfonyl)-2,3-Dihydroquinolin-4-One
CAS No.	857762-10-8
Molecular Formula	C₁₆H₁₂ClNO₃S
Molecular Weight	333.79 g/mol
Synonyms	6-Chloro-1-(4-methylphenyl)sulfonyl-2,3-dihydro-4(1H)-quinolinone; 6-Chloro-1-tosyl-2,3-dihydroquinolin-4(1H)-one; 6-Chloro-1-(p-toluenesulfonyl)-1,2,3,4-tetrahydro-4-oxoquinoline; 1-(4-Methylbenzenesulfonyl)-6-chloro-2,3-dihydro-4(1H)-quinolinone; 6-Chloro-1-(4-methylbenzenesulfonyl)-2,3-dihydroquinolin-4(1H)-one; 6-Chloro-1-tosyl-1,2,3,4-tetrahydro-4-oxoquinoline; 857762-10-8; 6-Chloro-1-(p-tolylsulfonyl)-2,3-dihydro-4(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-(p-Tolylsulfonyl)-2,3-Dihydroquinolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.