Description

Acetoacetic Acid, 4-Bromo-4-Hydroxy-, -γ--Lactone (5Ci) is a specialized brominated γ-lactone derivative, serving as a high-value synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both bromine and a lactone ring, makes it a critical building block for constructing complex molecules with precise stereochemistry and functional group diversity. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring bromine as a handle for further functionalization or as part of the active pharmacophore.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators that leverage its reactive bromine and lactone functionality.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials where the lactone moiety can influence polymer backbone properties.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes and tags used in biochemical and cellular research due to its modifiable structure.
• Asymmetric Synthesis: Valuable chiral synthon for constructing enantiomerically pure compounds in medicinal chemistry and catalysis research.
• Academic & Industrial R&D: Fundamental research chemical for exploring new organic reactions, methodologies, and catalytic processes in university and corporate laboratories.

Basic Information

Product Name	Acetoacetic Acid, 4-Bromo-4-Hydroxy-, -γ--Lactone (5Ci)
CAS No.	857559-59-2
Molecular Formula	C6H5BrO3
Molecular Weight	205.00 g/mol
Synonyms	4-Bromo-4-hydroxybut-2-en-4-olide; 4-Bromo-4-hydroxy-2H-furan-5-one; 5-Bromo-5-hydroxy-2(5H)-furanone; 4-Bromo-4-hydroxy-acetoacetic acid γ-lactone; 4-Bromo-4-hydroxy-2-buten-4-olide; 4-Bromo-4-hydroxybut-2-enolide; 4-Bromo-4-hydroxy-δα,β-butenolide
EINECS	Contact for details

Quality Control

Every batch of Acetoacetic Acid, 4-Bromo-4-Hydroxy-, -γ--Lactone (5Ci) is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.