Description

2-{[1-(3-Chloro-4-Fluorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drugs, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Protease Inhibitor Development: Serves as a core scaffold for the development of enzyme inhibitors targeting specific disease pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target validation.

Basic Information

Product Name	2-{[1-(3-Chloro-4-Fluorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid
CAS No.	857494-03-2
Molecular Formula	C16H10ClFN2O4S
Molecular Weight	380.78 g/mol
Synonyms	2-({[1-(3-Chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]thio})nicotinic acid; 2-[[1-(3-Chloro-4-fluorophenyl)-2,5-dioxopyrrolidin-3-yl]sulfanyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-[[1-(3-chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]-; 857494-03-2; 2-((1-(3-Chloro-4-fluorophenyl)-2,5-dioxopyrrolidin-3-yl)thio)nicotinic acid
EINECS	Contact for details

Quality Control

Our 2-{[1-(3-Chloro-4-Fluorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.