Description

5-Pyridin-3-Yl-Oxazole-2-Carboxylic Acid Ethyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new-generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions and organocatalysts due to its nitrogen-rich oxazole-pyridine structure.
• Material Science Research: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional organic compounds for electronic applications.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes and tool compounds to study biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific heterocyclic core.

Basic Information

Product Name	5-Pyridin-3-Yl-Oxazole-2-Carboxylic Acid Ethyl Ester
CAS No.	857334-87-3
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	Ethyl 5-(pyridin-3-yl)-1,3-oxazole-2-carboxylate; 5-(3-Pyridinyl)-2-oxazolecarboxylic Acid Ethyl Ester; 3-(2-Ethoxycarbonyloxazol-5-yl)pyridine; 857334-87-3; 5-(Pyridin-3-yl)oxazole-2-carboxylic acid ethyl ester; Ethyl 5-(3-pyridyl)oxazole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Pyridin-3-Yl-Oxazole-2-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full specification data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.