Description

tert-Butyl 4-[5-(Hydroxymethyl)Pyrid-2-Yl]Piperazine-1-Carboxylate is a high-value, multi-functional piperazine derivative and a key pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex drug candidates, particularly those targeting neurological disorders and cancer.
• API Synthesis: Used in the research and development stages for constructing the core piperazine-pyridine scaffold present in various bioactive molecules.
• Medicinal Chemistry Research: A valuable reagent for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for potential commercial APIs.
• Custom Synthesis: Acts as a starting material for the preparation of more complex, tailored intermediates for specific client projects.

Basic Information

Product Name	tert-Butyl 4-[5-(Hydroxymethyl)Pyrid-2-Yl]Piperazine-1-Carboxylate
CAS No.	857284-20-9
Molecular Formula	C15H23N3O3
Molecular Weight	293.36 g/mol
Synonyms	1-Boc-4-(5-(hydroxymethyl)pyridin-2-yl)piperazine; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-5-(hydroxymethyl)pyridine; tert-Butyl 4-(5-(hydroxymethyl)-2-pyridinyl)-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-[5-(hydroxymethyl)-2-pyridinyl]-, 1,1-dimethylethyl ester; 2-Piperazin-1-yl-5-hydroxymethyl-pyridine-1-carboxylic acid tert-butyl ester; BOC-Piperazine-Pyridine Intermediate; 857284-20-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[5-(Hydroxymethyl)Pyrid-2-Yl]Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and relevant industry guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.