Description

4-(4-Isocyanatophenyl)-2-Methyl-1,3-Thiazole is a specialized heterocyclic aromatic isocyanate monomer, identified by CAS NO 857283-94-4. This compound is a critical building block for synthesizing advanced polymers with tailored thermal, mechanical, and optical properties. It is primarily required by R&D chemists and material scientists in the pharmaceutical, agrochemical, and high-performance polymer industries for developing novel polyurethanes, polyureas, and other functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiazole and urea moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive isocyanate group for constructing bioactive molecules.
• Advanced Polymer Chemistry: A fundamental monomer for producing specialized polyurethanes and polyureas with enhanced durability, chemical resistance, and specific functional characteristics.
• Material Science R&D: Employed in creating novel coatings, adhesives, sealants, and elastomers (CASE) for demanding industrial applications.
• Liquid Crystal & OLED Materials: Acts as a building block for synthesizing organic semiconductors and liquid crystal compounds used in electronic displays.
• Cross-linking Agent: Functions as a reactive cross-linker in resin systems to improve thermal stability and mechanical strength.

Basic Information

Product Name	4-(4-Isocyanatophenyl)-2-Methyl-1,3-Thiazole
CAS No.	857283-94-4
Molecular Formula	C11H8N2OS
Molecular Weight	216.26 g/mol
Synonyms	4-(4-Isocyanatophenyl)-2-methylthiazole; 2-Methyl-4-(4-isocyanatophenyl)thiazole; 4-Isocyanatophenyl-2-methyl-1,3-thiazole; p-Isocyanatophenyl-2-methylthiazole; 2-Methyl-4-(p-isocyanatophenyl)thiazole; 4-(2-Methyl-1,3-thiazol-4-yl)phenyl isocyanate
EINECS	Contact for details

Quality Control

Our 4-(4-Isocyanatophenyl)-2-Methyl-1,3-Thiazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and polymerization. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.