Description

1-(3-Isocyanatophenyl)-1H-Pyrrole is a specialized aromatic isocyanate derivative that serves as a high-value building block in advanced organic synthesis. Its core value lies in its dual functionality, combining a reactive isocyanate group with a pyrrole heterocycle, enabling the creation of novel polymers and fine chemicals with tailored properties. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system disorders.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides with enhanced efficacy and environmental profiles.
• Polymer & Resin Modification: Serves as a cross-linking agent or monomer for producing polyurethanes, polyureas, and other specialty polymers with unique thermal or mechanical properties.
• Material Science Research: Employed in developing functional coatings, adhesives, and electronic materials that require specific chemical resistance or binding characteristics.
• Ligand & Catalyst Development: The pyrrole moiety can be utilized to construct complex ligands for catalytic systems in asymmetric synthesis.
• Chemical Library Production: A valuable scaffold for combinatorial chemistry and high-throughput screening in drug discovery programs.

Basic Information

Product Name	1-(3-Isocyanatophenyl)-1H-Pyrrole
CAS No.	857283-59-1
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	3-(1H-Pyrrol-1-yl)phenyl isocyanate; 1H-Pyrrole, 1-[3-(isocyanato)phenyl]-; 3-Isocyanato-1-(1H-pyrrol-1-yl)benzene; 1-(3-Isocyanophenyl)pyrrole; m-Isocyanatophenylpyrrole; NSC 405124; 1-(m-Isocyanatophenyl)pyrrole; 3-(Pyrrol-1-yl)phenyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Isocyanatophenyl)-1H-Pyrrole is manufactured and tested under strict quality management protocols to ensure consistency and purity for critical R&D and production applications. Our quality assurance includes comprehensive analytical testing via HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.