Description

4-(Methylsulfonyl)Pyridin-3-Amine is a high-purity sulfonylpyridine derivative, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both an amine and a methylsulfonyl group on the pyridine ring, makes it an essential intermediate for creating complex molecules with targeted functionalities. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Serves as a foundational structure for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the synthesis of specialized ligands, catalysts, and functional polymers for advanced material applications.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Bioconjugation & Probe Development: The reactive amine group allows for its use in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	4-(Methylsulfonyl)Pyridin-3-Amine
CAS No.	857220-38-3
Molecular Formula	C6H8N2O2S
Molecular Weight	172.21 g/mol
Synonyms	3-Amino-4-(methylsulfonyl)pyridine; 4-Methanesulfonylpyridin-3-amine; 4-Methylsulfonyl-3-aminopyridine; 3-Pyridinamine, 4-(methylsulfonyl)-; 4-(Methylsulfonyl)-3-pyridinamine
EINECS	Contact for details

Quality Control

Our 4-(Methylsulfonyl)Pyridin-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.