Description

Methyl 2-Amino-2-(5-Bromopyridin-3-Yl)Hexanoate CAS NO 856886-54-9 is a high-value, non-natural amino acid ester derivative featuring a brominated pyridine moiety. This compound is a critical chiral building block and intermediate in modern pharmaceutical synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Agrochemical Synthesis: Used in the creation of advanced, targeted pesticides and herbicides where the bromopyridine unit acts as a bioactive core.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Acts as a constrained amino acid analog for designing peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Item	Details
Product Name	Methyl 2-Amino-2-(5-Bromopyridin-3-Yl)Hexanoate
CAS No.	856886-54-9
Molecular Formula	C13H17BrN2O2
Molecular Weight	313.19 g/mol
Synonyms	2-Amino-2-(5-bromo-3-pyridinyl)hexanoic acid methyl ester; Methyl 2-amino-2-(5-bromopyridin-3-yl)hexanoate; 5-Bromo-3-pyridineacetic acid, α-amino-α-ethyl-, methyl ester; (5-Bromopyridin-3-yl)glycine derivative; 856886-54-9; Methyl α-amino-α-ethyl-5-bromonicotinate; 2-(5-Bromopyridin-3-yl)-2-aminocaproic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-2-(5-Bromopyridin-3-Yl)Hexanoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical R&D and scale-up. A Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.