Description

3-(5-Bromo-2-Pyridinyl)-5-Isoxazolemethanol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its bromopyridine and isoxazole motifs.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic & Industrial R&D: Used in exploratory chemistry within university laboratories and corporate R&D centers for novel heterocyclic chemistry.

Basic Information

Product Name	3-(5-Bromo-2-Pyridinyl)-5-Isoxazolemethanol
CAS No.	856867-66-8
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	5-(Hydroxymethyl)-3-(5-bromopyridin-2-yl)isoxazole; 3-(5-Bromo-2-pyridyl)-5-isoxazolemethanol; 5-Bromo-2-(5-(hydroxymethyl)isoxazol-3-yl)pyridine; (5-Bromo-2-pyridin-2-yl)-1,2-oxazol-5-ylmethanol; 856867-66-8; 3-(5-Bromopyridin-2-yl)-5-(hydroxymethyl)isoxazole
EINECS	Contact for details

Quality Control

Our 3-(5-Bromo-2-Pyridinyl)-5-Isoxazolemethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP and ISO 9001 standards for pharmaceutical and industrial applications, ensuring traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.