Description

(R)-3-(3-Fluoro-4-(6-(1-Methyl-1H-Tetrazol-5-Yl)Pyridin-3-Yl) Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of next-generation antibacterial agents. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on developing innovative therapeutic solutions.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel oxazolidinone-class antibacterial agents.
• Antibacterial Drug Development: Used in R&D for creating new antibiotics targeting resistant bacterial strains.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the scale-up and process development for new Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Applied in studies investigating bacterial protein synthesis inhibition mechanisms.

Basic Information

Product Name	(R)-3-(3-Fluoro-4-(6-(1-Methyl-1H-Tetrazol-5-Yl)Pyridin-3-Yl) Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One
CAS No.	856867-41-9
Molecular Formula	C17H15FN6O3
Molecular Weight	370.34 g/mol
Synonyms	(R)-Tedizolid Intermediate; (R)-TR-700; (R)-3-[3-Fluoro-4-[6-(1-methyl-1H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone; (R)-Tedizolid Phosphate Impurity; (R)-DA-7157; (R)-Oxazolidinone Antibacterial Intermediate; (R)-3-(3-Fluoro-4-(6-(1-Methyl-1H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (R)-3-(3-Fluoro-4-(6-(1-Methyl-1H-Tetrazol-5-Yl)Pyridin-3-Yl) Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (R-enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.