Description

4-Bromo-1H-Pyrazolo[3,4-B]Pyridine CAS NO 856859-49-9 is a high-purity brominated heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a versatile intermediate for the synthesis of complex molecules, enabling the exploration of novel biological activities. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products, such as herbicides and fungicides.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study enzyme function and cellular signaling.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates under cGMP conditions.

Basic Information

Product Name	4-Bromo-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	856859-49-9
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	4-Bromo-1H-pyrazolo[3,4-b]pyridine; 4-Bromo-1H-pyrazolo[3,4-b]pyridine; 4-Bromo-1H-pyrazolo[3,4-b]pyridine; 4-Bromo-1H-pyrazolo[3,4-b]pyridine; 4-Bromopyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 4-bromo-; 856859-49-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥97% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material suitable for research use and can supply grades compliant with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.