Description

2,4,5-Tribromopyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), ligands, and functional materials. Its specific substitution pattern offers unique reactivity for selective cross-coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its bromine atoms for structural diversity.
• Ligand and Catalyst Development: Employed in the creation of specialized nitrogen-containing ligands for transition metal catalysis.
• Material Science Research: Acts as a monomer or functional unit in the synthesis of organic electronic materials, such as charge-transport layers.
• Chemical Biology Probes: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2,4,5-Tribromopyridine
CAS No.	856857-52-8
Molecular Formula	C5H2Br3N
Molecular Weight	315.79 g/mol
Synonyms	Pyridine, 2,4,5-tribromo-; 2,4,5-TBP; Tribromopyridine; NSC 406911; 2,4,5-Tribromo-pyridine; AI3-52711; 2,4,5-Tribromopyridine (8CI)
EINECS	Contact for details

Quality Control

Our 2,4,5-Tribromopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.