Description

5-Nitro-2-(o-Tolyloxy)Pyridine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its unique nitro and aryloxy substituents offer versatile sites for further chemical modification. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel molecular entities.

Application

• As a crucial pharmaceutical intermediate in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Utilized in agrochemical research for the development of novel herbicides and pesticides.
• Serves as a key building block in organic synthesis for constructing complex heterocyclic frameworks.
• Used in material science research for the creation of functional dyes, ligands, and advanced polymers.
• Acts as a precursor in the synthesis of more complex pyridine derivatives with tailored biological or physical properties.
• Employed in academic and industrial R&D for method development and exploration of new chemical reactions.

Basic Information

Product Name	5-Nitro-2-(o-Tolyloxy)Pyridine
CAS No.	856855-81-7
Molecular Formula	C₁₂H₁₀N₂O₃
Molecular Weight	230.22 g/mol
Synonyms	2-(2-Methylphenoxy)-5-nitropyridine; 5-Nitro-2-(2-methylphenoxy)pyridine; 2-(o-Tolyloxy)-5-nitropyridine; Pyridine, 2-(2-methylphenoxy)-5-nitro-; 856855-81-7; 5-Nitro-2-(2-methylphenoxy)pyridine; 2-(2-Methylphenoxy)-5-nitro-pyridine
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(o-Tolyloxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.