Description

4-Chloro-2-Ethoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the chloro and ethoxy substituents, which enable selective functionalization for creating complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	4-Chloro-2-Ethoxypyridine
CAS No.	856851-45-1
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	2-Ethoxy-4-chloropyridine; 4-Chloro-2-ethoxypyridine; Pyridine, 4-chloro-2-ethoxy-; 4-Chloro-2-ethoxy-pyridine; 2-Ethoxy-4-chloro-pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Ethoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.