Description

3-Chloro-6-Methoxypyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is prized for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular construction. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly in developing kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up activities.
• Academic and R&D Laboratories: Used in medicinal chemistry and synthetic chemistry research for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Chloro-6-Methoxypyridine-2-Carboxylic Acid
CAS No.	856836-44-7
Molecular Formula	C7H6ClNO3
Molecular Weight	187.58 g/mol
Synonyms	2-Carboxy-3-chloro-6-methoxypyridine; 3-Chloro-6-methoxy-2-pyridinecarboxylic acid; 3-Chloro-6-methoxypicolinic acid; 6-Methoxy-3-chloropicolinic acid; 3-Chloro-6-methoxypyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 3-chloro-6-methoxy-; Picolinic acid, 3-chloro-6-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Methoxypyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.