Description

2-(Chloromethyl)-5-(Trifluoromethyl)Pyridine Hydrochloride is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its reactive chloromethyl and electron-deficient pyridine core, making it a versatile building block for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Custom Chemical Synthesis: Provides a critical scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	2-(Chloromethyl)-5-(Trifluoromethyl)Pyridine Hydrochloride
CAS No.	856250-59-4
Molecular Formula	C7H6Cl2F3N
Molecular Weight	236.03 g/mol
Synonyms	5-(Trifluoromethyl)-2-(chloromethyl)pyridine hydrochloride; 2-Chloromethyl-5-trifluoromethylpyridine hydrochloride; 2-Pyridinemethanol, 5-(trifluoromethyl)-, hydrochloride (1:1), 2-chloro-; (5-Trifluoromethyl-2-pyridyl)methyl chloride hydrochloride; 2-(Chloromethyl)-5-(trifluoromethyl)pyridine HCl; 5-(Trifluoromethyl)-2-pyridylmethyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-5-(Trifluoromethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.