Description

n-Hydroxy-Nicotinamidine is a versatile organic compound belonging to the class of amidoximes, characterized by its functional hydroxyl and amidine groups attached to a pyridine ring. This unique structure makes it a valuable building block and intermediate for synthesizing more complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists working on novel active ingredients, metal chelators, and functional materials. The compound, CAS NO 856213-45-1, offers a critical handle for introducing specific reactivity into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the amidoxime moiety is pharmacologically active.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides, leveraging its ability to chelate metals or act as a bioisostere.
• Coordination Chemistry & Ligand Synthesis: Serves as a bidentate ligand for complexing various metal ions, useful in catalysis, material science, and analytical chemistry.
• Chemical Biology Probes: Employed in creating molecular probes to study biological processes due to its specific binding and reactive properties.
• Polymer Modification: Functional monomer for incorporating specific chelating or reactive sites into polymer chains.
• Organic Synthesis Building Block: Versatile intermediate for constructing heterocyclic compounds like oxadiazoles, triazoles, and other nitrogen-containing rings.

Basic Information

Product Name	n-Hydroxy-Nicotinamidine
CAS No.	856213-45-1
Molecular Formula	C6H7N3O
Molecular Weight	137.14 g/mol
Synonyms	Nicotinamide oxime; 3-Pyridinecarboximidamide, N-hydroxy-; N-Hydroxynicotinamidine; Pyridine-3-carboxamidoxime; 3-(N-Hydroxycarbamimidoyl)pyridine; 3-Pyridylamidoxime; Amidoxime derivative of nicotinic acid
EINECS	Contact for details

Quality Control

Our n-Hydroxy-Nicotinamidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting R&D and process chemistry standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.