Description

3-Pyridinecarboxylic Acid, 6-Chloro-5-Cyano-, Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates chloro, cyano, and ester functionalities on a pyridine scaffold, enabling precise chemical modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or components for organic light-emitting diodes (OLEDs).
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector, enabling the production of bespoke molecules for client projects.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 6-Chloro-5-Cyano-, Ethyl Ester
CAS No.	856165-97-4
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	6-Chloro-5-cyano-nicotinic acid ethyl ester; Ethyl 6-chloro-5-cyano-3-pyridinecarboxylate; 6-Chloro-5-cyanopyridine-3-carboxylic acid ethyl ester; 3-Carbethoxy-6-chloro-5-cyanopyridine; 6-Chloro-5-cyano-3-pyridinecarboxylic acid ethyl ester; Ethyl 6-chloro-5-cyanonicotinate; 6-Chloro-5-cyanonicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 6-Chloro-5-Cyano-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.