Description

2-Pyridineacetamide, 3-Chloro-n-[(1R)-1-(3-Chlorophenyl)Ethyl]-6-[[2,2-Difluoro-2-(1-Oxido-2-Pyridinyl)Ethyl]Amino]-, 1-Oxide is a sophisticated, high-purity chiral organic compound featuring a complex pyridine-based structure with multiple functional groups. This molecule is of significant commercial interest as a key advanced pharmaceutical intermediate (API) or a pharmacologically active scaffold in modern drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for applications in oncology, neurology, and anti-inflammatory treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for clinical research and development.
• Drug Discovery Scaffold: Used in medicinal chemistry for structure-activity relationship (SAR) studies and high-throughput screening to identify new drug candidates.
• Biochemical Research: Employed as a reference standard or a probe compound in biochemical and pharmacological assays to study enzyme inhibition or receptor binding.
• Chemical Synthesis: Acts as a versatile chiral synthon for the preparation of more complex, target-oriented molecules in organic chemistry laboratories.
• Agrochemical Research: Potential application as a precursor in the development of new, high-efficacy crop protection agents.

Basic Information

Product Name	2-Pyridineacetamide, 3-Chloro-n-[(1R)-1-(3-Chlorophenyl)Ethyl]-6-[[2,2-Difluoro-2-(1-Oxido-2-Pyridinyl)Ethyl]Amino]-, 1-Oxide
CAS No.	855998-46-8
Molecular Formula	C22H20Cl2F2N4O3
Molecular Weight	485.32 g/mol
Synonyms	3-Chloro-N-[(1R)-1-(3-chlorophenyl)ethyl]-6-[[2,2-difluoro-2-(1-oxido-2-pyridinyl)ethyl]amino]-2-pyridineacetamide 1-oxide; (R)-3-Chloro-N-(1-(3-chlorophenyl)ethyl)-6-((2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl)amino)picolinamide 1-oxide; CAS 855998-46-8; 855998-46-8; Chiral Pyridineacetamide Derivative; Difluoropyridinyl Amino Picolinamide Oxide
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC (for assay and impurity profile), Chiral HPLC (for enantiomeric excess), NMR, and MS. We support cGMP compliance for advanced applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.