Description

2-[[(5-Methylisoxazol-3-Yl)Methyl]Thio]Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic architectures. It is primarily sought by research institutions and manufacturers in the global pharmaceutical, agrochemical, and fine chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and inflammatory pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile synthon for constructing more complex molecules in medicinal and organic chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory research and method development.
• Process Chemistry & Scale-Up: Integral to optimizing synthetic routes and scaling production from lab to pilot plant and commercial manufacturing.

Basic Information

Product Name	2-[[(5-Methylisoxazol-3-Yl)Methyl]Thio]Nicotinic Acid
CAS No.	855991-78-5
Molecular Formula	C11H10N2O3S
Molecular Weight	250.27 g/mol
Synonyms	2-(((5-Methylisoxazol-3-yl)methyl)thio)nicotinic acid; 2-(((5-Methyl-3-isoxazolyl)methyl)thio)-3-pyridinecarboxylic acid; Nicotinic acid, 2-[[(5-methyl-3-isoxazolyl)methyl]thio]-; 2-[(5-Methylisoxazol-3-ylmethyl)sulfanyl]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-[[(5-Methylisoxazol-3-Yl)Methyl]Thio]Nicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.