Description

6-Chloro-5-(2,2,2-trifluoroethoxy)picolinic acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated picolinic acid structure. This compound is of significant commercial importance as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of next-generation products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting specific enzyme pathways.
• Agrochemical Research: Serves as a foundational structure for developing new herbicides and plant growth regulators with enhanced efficacy.
• Chemical Synthesis: Used as a versatile building block in organic chemistry for constructing heterocyclic compounds and introducing the trifluoroethoxy functional group.
• Material Science: Potential application in the research and development of specialty chemicals and advanced materials.

Basic Information

Product Name	6-Chloro-5-(2,2,2-trifluoroethoxy)picolinic Acid
CAS No.	855916-43-7
Molecular Formula	C8H5ClF3NO3
Molecular Weight	255.58 g/mol
Synonyms	6-Chloro-5-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-chloro-5-(2,2,2-trifluoroethoxy)-; 5-(2,2,2-Trifluoroethoxy)-6-chloropicolinic acid; 6-Chloro-5-(trifluoroethoxy)picolinic acid; 6-Chloro-5-(2,2,2-trifluoroethoxy)-2-pyridinecarboxylic acid; Picolinic acid, 6-chloro-5-(2,2,2-trifluoroethoxy)-; CAS 855916-43-7
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-(2,2,2-trifluoroethoxy)picolinic acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.