Description

6-Methyl-5-(Trifluoromethyl)Picolinic Acid is a high-purity, multi-functional heterocyclic building block of significant commercial interest. Its core value lies in its unique trifluoromethylated picolinic acid structure, which is highly sought after for imparting desirable metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, serving as a critical intermediate in the synthesis of advanced active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand for Catalysis: Serves as a precursor for creating specialized ligands used in transition metal-catalyzed cross-coupling reactions, crucial for fine chemical manufacturing.
• Material Science Research: Investigated as a building block for advanced organic materials, including polymers and liquid crystals with specific electronic properties.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	6-Methyl-5-(Trifluoromethyl)Picolinic Acid
CAS No.	855916-28-8
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	5-(Trifluoromethyl)-6-picolinic acid; 6-Methyl-5-(trifluoromethyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-methyl-5-(trifluoromethyl)-; 5-Trifluoromethyl-6-methylpicolinic acid; 6-Methyl-5-trifluoromethylpicolinic acid; 855916-28-8; 6-Methyl-5-(trifluoromethyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Methyl-5-(Trifluoromethyl)Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.