Description

6-Oxo-5-(Trifluoromethyl)-1,6-Dihydropyridine-2-Carboxylic Acid is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring a trifluoromethyl group and a carboxylic acid handle, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals with enhanced metabolic stability and bioavailability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules. The compound is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for your critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for incorporating the metabolically stable trifluoromethyl group into heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine moiety can improve efficacy and environmental profile.
• Ligand and Catalyst Development: The carboxylic acid and pyridone functionalities make it a useful precursor for designing novel chelating ligands and organocatalysts.
• Material Science Research: Employed in the synthesis of specialized fluorinated polymers or organic electronic materials that require specific heterocyclic components.
• Chemical Biology Probes: Acts as a building block for creating fluorescent tags or activity-based probes used in biochemical and cellular studies.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	6-Oxo-5-(Trifluoromethyl)-1,6-Dihydropyridine-2-Carboxylic Acid
CAS No.	855915-13-8
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	5-(Trifluoromethyl)-2-pyridone-6-carboxylic acid; 5-(Trifluoromethyl)-6-oxo-1,6-dihydropyridine-2-carboxylic acid; 2-Carboxy-5-(trifluoromethyl)-2-hydroxypyridine; 1,6-Dihydro-5-(trifluoromethyl)-6-oxo-2-pyridinecarboxylic acid; 5-Trifluoromethyl-6-oxo-1,6-dihydro-pyridine-2-carboxylic acid; TFMP-2-COOH; 855915-13-8
EINECS	Contact for details

Quality Control

Our 6-Oxo-5-(Trifluoromethyl)-1,6-Dihydropyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.