Description

6-Methyl-5-(trifluoromethyl)-2-pyridinecarboxylic acid ethyl ester is a high-value fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethyl group and an ethyl ester moiety, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity, metabolic stability, and overall efficacy.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of advanced organic materials, including liquid crystals and organic semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	6-Methyl-5-(trifluoromethyl)-2-pyridinecarboxylic acid ethyl ester
CAS No.	855911-75-0
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Ethyl 6-methyl-5-(trifluoromethyl)picolinate; 5-(Trifluoromethyl)-6-methylpicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 6-methyl-5-(trifluoromethyl)-, ethyl ester; Ethyl 6-methyl-5-(trifluoromethyl)-2-pyridinecarboxylate; 855911-75-0; 6-Methyl-5-trifluoromethyl-pyridine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Methyl-5-(trifluoromethyl)-2-pyridinecarboxylic acid ethyl ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.