Description

2-Chloro-4-Isocyanato-Pyridine is a versatile and highly reactive aromatic isocyanate building block, essential for constructing complex molecular architectures. Its core value lies in enabling the efficient synthesis of pyridine-based ureas, carbamates, and other heterocyclic compounds through its reactive isocyanate group. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in advanced material science for creating functional polymers and ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides with pyridine cores.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating polyurethanes, polyureas, and other specialty polymers with enhanced properties.
• Chemical Research & Development: A crucial reagent for medicinal chemistry, facilitating the rapid exploration of structure-activity relationships (SAR).
• Ligand & Catalyst Design: Used to synthesize sophisticated pyridine-containing ligands for coordination chemistry and catalytic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Chloro-4-Isocyanato-Pyridine
CAS No.	855773-46-5
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	4-Isocyanato-2-chloropyridine; 2-Chloro-4-pyridyl isocyanate; 2-Chloro-4-isocyanatopyridine; 2-Chloro-4-pyridinyl isocyanate; Isocyanic acid, 2-chloro-4-pyridinyl ester; 2-Chloro-4-pyridine isocyanate
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Isocyanato-Pyridine is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.