Description

2-Mercapto-1-Oxy-Isonicotinic Acid Methyl Ester is a specialized heterocyclic building block featuring both a reactive thiol (mercapto) group and an ester moiety. This compound is valued for its versatility as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Peptide Mimetics: The thiol and ester functionalities allow its incorporation into peptide analogs and protease inhibitors.
• Material Science: Employed in the research of functional polymers and organic electronic materials due to its modifiable structure.
• Chemical Biology Probes: Useful for synthesizing probes that study enzyme function and protein interactions.

Basic Information

Product Name	2-Mercapto-1-Oxy-Isonicotinic Acid Methyl Ester
CAS No.	855636-34-9
Molecular Formula	C7H7NO3S
Molecular Weight	185.20 g/mol
Synonyms	Methyl 2-mercapto-1-oxo-1,2-dihydroisonicotinate; 2-Mercapto-1-oxo-1,2-dihydroisonicotinic acid methyl ester; 1,2-Dihydro-2-mercapto-1-oxo-4-pyridinecarboxylic acid methyl ester; 2-Sulfanyl-1-oxidanylidene-1,2-dihydropyridine-4-carboxylic acid methyl ester; 4-Pyridinecarboxylic acid, 1,2-dihydro-2-mercapto-1-oxo-, methyl ester; Methyl 1,2-dihydro-2-mercapto-1-oxoisonicotinate
EINECS	Contact for details

Quality Control

Our 2-Mercapto-1-Oxy-Isonicotinic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.