Description

7-Methoxy-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate belonging to the imidazopyridine class of heterocyclic compounds. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is essential for research and development chemists, process scale-up engineers, and manufacturers in the global pharmaceutical and biotechnology sectors seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, especially those with activity in the central nervous system (CNS).
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for the research and development of new therapeutic agents.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Medicinal Chemistry Research: Used in academic and industrial R&D labs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in developing and optimizing robust, cost-effective synthetic pathways from laboratory to pilot plant and commercial production scales.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	7-Methoxy-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	854515-82-5
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	Ethyl 7-Methoxy-2-methylimidazo[1,2-a]pyridine-3-carboxylate; 7-Methoxy-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-3-carboxylic acid, 7-methoxy-2-methyl-, ethyl ester; 854515-82-5; Ethyl 7-methoxy-2-methyl-imidazo[1,2-a]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Methoxy-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.