Description

4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine is a high-purity, heterocyclic organic compound featuring a fused isoxazole-pyridine core structure with a trifluoromethyl substituent. This molecule is of significant commercial interest as a key advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Medicinal Chemistry Research: A valuable scaffold for constructing compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Fluorinated Compound Production: Acts as a specialized precursor for introducing the trifluoromethyl group into more complex molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine
CAS No.	853784-23-3
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	3-(Trifluoromethyl)-4,5,6,7-tetrahydroisoxazolo[3,4-c]pyridine; 4,5,6,7-Tetrahydro-3-(trifluoromethyl)-isoxazolo[3,4-c]pyridine; Isoxazolo[3,4-c]pyridine, 4,5,6,7-tetrahydro-3-(trifluoromethyl)-; 853784-23-3; 3-Trifluoromethyl-4,5,6,7-tetrahydroisoxazolo[3,4-c]pyridine
EINECS	Contact for details

Quality Control

Our production of 4,5,6,7-Tetrahydro-3-(trifluoromethyl)isoxazolo[3,4-c]pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems support development from research to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.