Description

3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine is a high-value, heterocyclic organic compound featuring a fused pyrazole-pyridine core with a trifluoromethyl substituent. This structure is critical for its role as a versatile and potent building block in modern pharmaceutical discovery and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients. The compound, identified by CAS number 853784-21-1, enables the modulation of key biological properties such as metabolic stability, lipophilicity, and binding affinity in target molecules.

Application

This advanced chemical intermediate is engineered for precision applications in research and development. Its primary uses include:

• Pharmaceutical Intermediate: A key scaffold for developing novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the synthesis of new-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Biology & Proteomics: Serves as a core structure for designing chemical probes and enzyme inhibitors to study biological pathways.
• Material Science Research: Investigated as a precursor for specialty polymers and advanced organic electronic materials due to its unique electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and library production for high-throughput screening.

Basic Information

Product Name	3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine
CAS No.	853784-21-1
Molecular Formula	C7H8F3N3
Molecular Weight	191.16 g/mol
Synonyms	3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine; 1H-Pyrazolo[3,4-c]pyridine, 4,5,6,7-tetrahydro-3-(trifluoromethyl)-; 853784-21-1; 3-Trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine; 4,5,6,7-Tetrahydro-3-(trifluoromethyl)-1H-pyrazolo[3,4-c]pyridine; Pyrazolopyridine trifluoromethyl derivative; TFMPP intermediate.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to meet the exacting standards of pharmaceutical and agrochemical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.