Description

Rac n-tert-Butoxycarbonyl-2-Fluoro-5-Methoxy-4-o-Methyl-Tyrosine Methyl Ester is a protected, fluorinated tyrosine derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in introducing a modified tyrosine scaffold into target molecules, enabling the exploration of structure-activity relationships in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, enzyme inhibitors, and radiopharmaceuticals. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide analogs and potential active pharmaceutical ingredients (APIs).
• Proteomics & Biochemistry Research: Used to incorporate fluorinated and methoxy-substituted tyrosine residues into peptides for studying protein structure, function, and interactions.
• Medicinal Chemistry: Serves as a versatile building block for creating focused libraries of compounds in drug discovery programs targeting various enzymes and receptors.
• Positron Emission Tomography (PET) Tracer Development: The fluorine atom and aromatic structure make it a candidate scaffold for developing F-18 labeled radiotracers for diagnostic imaging.
• Chemical Biology Tool Development: Employed in the synthesis of activity-based probes and affinity labels to study biological pathways.

Basic Information

Product Name	Rac n-tert-Butoxycarbonyl-2-Fluoro-5-Methoxy-4-o-Methyl-Tyrosine Methyl Ester
CAS No.	853759-57-6
Molecular Formula	C₁₇H₂₄FNO₆
Molecular Weight	357.38 g/mol
Synonyms	Boc-2-Fluoro-5-Methoxy-4-methyl-DL-tyrosine Methyl Ester; Methyl (RS)-2-((tert-Butoxycarbonyl)amino)-3-(2-fluoro-5-methoxy-4-methylphenyl)propanoate; DL-2-Fluoro-5-Methoxy-4-methyltyrosine Methyl Ester N-Boc Derivative; Boc-DL-FmTyr(Me)-OMe; N-Boc-2-Fluoro-5-Methoxy-4-methyltyrosine Methyl Ester; (RS)-2-(tert-Butoxycarbonylamino)-3-(2-fluoro-5-methoxy-4-methylphenyl)propionic Acid Methyl Ester; 853759-57-6
EINECS	Contact for details

Quality Control

Our Rac n-tert-Butoxycarbonyl-2-Fluoro-5-Methoxy-4-o-Methyl-Tyrosine Methyl Ester is manufactured under controlled conditions to ensure high chemical purity and lot-to-lot reproducibility suitable for research and development. Each batch is subjected to rigorous analytical testing, including HPLC, 1H/13C NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.