Description

Methyl 2-Amino-2-Benzylhexanoate is a high-purity chiral building block and synthetic intermediate of significant commercial importance. Its unique structure, featuring both amino and ester functional groups on a chiral center, makes it a valuable precursor in the synthesis of complex pharmaceutical compounds and fine chemicals. This product is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorder treatments.
• Peptidomimetic Research: Serves as a constrained amino acid analog for the design and synthesis of novel peptide-based drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced, chiral herbicides and pesticides with improved efficacy and environmental profiles.
• Catalyst Ligand Precursor: Employed in the preparation of chiral ligands for asymmetric catalysis in fine chemical manufacturing.
• Academic & Industrial R&D: A valuable compound for methodological development in organic synthesis and medicinal chemistry research programs.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research and manufacturing organizations (CROs/CMOs) producing custom molecules for clients.

Basic Information

Product Name	Methyl 2-Amino-2-Benzylhexanoate
CAS No.	853303-77-2
Molecular Formula	C15H23NO2
Molecular Weight	249.35 g/mol
Synonyms	2-Amino-2-benzylhexanoic acid methyl ester; Methyl 2-amino-2-benzylcaproate; 2-Benzyl-2-aminocaproic acid methyl ester; (RS)-Methyl 2-amino-2-benzylhexanoate; DL-Methyl 2-amino-2-benzylhexanoate; α-Amino-α-benzylcaproic acid methyl ester; Methyl α-amino-α-benzylhexanoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-2-Benzylhexanoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.