Description

2-Bromo-6-Methoxy-4-Pyridinecarboxylic Acid Methyl Ester is a high-purity, versatile pyridine derivative building block essential for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key intermediate in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromo and methoxy functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic and Institutional Research: Used in university and government laboratories for methodological studies and exploring new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	2-Bromo-6-Methoxy-4-Pyridinecarboxylic Acid Methyl Ester
CAS No.	853030-09-8
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	Methyl 2-bromo-6-methoxypyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-bromo-6-methoxy-, methyl ester; 2-Bromo-6-methoxyisonicotinic acid methyl ester; 6-Methoxy-2-bromo-4-pyridinecarboxylic acid methyl ester; Methyl 2-bromo-6-methoxyisonicotinate
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Methoxy-4-Pyridinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.