Description

4-(Hydroxymethyl)-2,6-Pyridinedicarboxylic Acid 2,6-Dimethyl Ester is a high-purity pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, offering both a hydroxymethyl group and ester functionalities for selective chemical transformations. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridine-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require a functionalized pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic materials, such as polymers and liquid crystals, where the pyridine moiety imparts specific electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for biological imaging and diagnostic applications.

Basic Information

Product Name	4-(Hydroxymethyl)-2,6-Pyridinedicarboxylic Acid 2,6-Dimethyl Ester
CAS No.	852936-60-8
Molecular Formula	C11H11NO5
Molecular Weight	237.21 g/mol
Synonyms	2,6-Bis(methoxycarbonyl)-4-pyridinemethanol; 4-(Hydroxymethyl)pyridine-2,6-dicarboxylic acid dimethyl ester; Dimethyl 4-(hydroxymethyl)pyridine-2,6-dicarboxylate; 4-Pyridinemethanol, 2,6-bis(methoxycarbonyl)-; 2,6-Pyridinedicarboxylic acid, 4-(hydroxymethyl)-, dimethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(Hydroxymethyl)-2,6-Pyridinedicarboxylic Acid 2,6-Dimethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.