Description

4-Chloro-2-(Piperidine-1-Carbonyl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine core functionalized with a chloro substituent and a piperidine carbonyl moiety. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable compound for university laboratories conducting research in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4-Chloro-2-(Piperidine-1-Carbonyl)Pyridine
CAS No.	852851-85-5
Molecular Formula	C11H13ClN2O
Molecular Weight	224.69 g/mol
Synonyms	4-Chloro-2-(1-piperidinecarbonyl)pyridine; 2-Pyridinecarboxamide, 4-chloro-N-1-piperidinyl-; 4-Chloro-N-(piperidin-1-yl)picolinamide; 852851-85-5; 4-Chloro-2-piperidine-1-carbonyl-pyridine; 4-Chloro-2-(piperidine-1-carbonyl)pyridine; 4-Chloro-2-(1-piperidylcarbonyl)pyridine; N-(Piperidin-1-yl)-4-chloropicolinamide
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-(Piperidine-1-Carbonyl)Pyridine is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.