Description

1H-Imidazo[4,5-B]Pyridine, 1-(4-Piperidinyl)- is a high-value, nitrogen-rich heterocyclic compound with a fused imidazopyridine core, serving as a critical advanced pharmaceutical intermediate. Its precise molecular architecture makes it an essential building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at research institutions and pharmaceutical companies engaged in developing new therapeutic agents, particularly in areas like kinase inhibitors and central nervous system (CNS) drugs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study biological pathways and validate novel drug targets.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	1H-Imidazo[4,5-B]Pyridine, 1-(4-Piperidinyl)-
CAS No.	852627-76-0
Molecular Formula	C11H14N4
Molecular Weight	202.26 g/mol
Synonyms	1-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridine; 1-(4-Piperidyl)-1H-imidazo[4,5-b]pyridine; 1-(Piperidin-4-yl)imidazo[4,5-b]pyridine; 852627-76-0; 1H-Imidazo[4,5-b]pyridine, 1-(4-piperidinyl)-; 1-(4-Piperidinyl)-1H-imidazo[4,5-b]pyridine; 1-Piperidin-4-yl-1H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazo[4,5-B]Pyridine, 1-(4-Piperidinyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.