Description

3-(2,4-Dioxo-1,3-Diaza-Spiro[4.4]Non-3-Yl)-Propionic Acid is a high-value, heterocyclic building block featuring a unique spirocyclic structure. This compound is critical for advanced organic synthesis, serving as a versatile precursor for creating complex molecules with tailored properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Organic Synthesis Building Block: Used to construct complex spirocyclic and heterocyclic frameworks prevalent in modern medicinal chemistry and agrochemicals.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Serves as a core structure for developing enzyme inhibitors or molecular probes to study biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	3-(2,4-Dioxo-1,3-Diaza-Spiro[4.4]Non-3-Yl)-Propionic Acid
CAS No.	852400-00-1
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	3-(2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl)propanoic acid; 3-(2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl)propionic Acid; 1,3-Diazaspiro[4.4]nonane-2,4-dione, 3-(2-carboxyethyl)-; 3-(2,4-Dioxo-1,3-diaza-spiro[4.4]non-3-yl)-propionic acid; Propanoic acid, 3-(2,4-dioxo-1,3-diazaspiro[4.4]non-3-yl)-; CAS 852400-00-1
EINECS	Contact for details

Quality Control

Our 3-(2,4-Dioxo-1,3-Diaza-Spiro[4.4]Non-3-Yl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.