Description

5-(3-Chlorophenyl)-2-Piperidin-1-Yl[1,3]Thiazolo[4,5-B]Pyridine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical entity to develop and scale up production of next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the research and development of new drug molecules.
• API Synthesis: Used as a key building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Enables exploration of structure-activity relationships (SAR) in drug discovery programs, particularly for kinase inhibitors or other targeted therapies.
• Preclinical Development: Supports the production of material for pharmacological and toxicological studies.
• Chemical Biology Probes: Can be utilized to create specialized probes for studying biological pathways and target engagement.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for cGMP production of clinical trial materials.

Basic Information

Product Name	5-(3-Chlorophenyl)-2-Piperidin-1-Yl[1,3]Thiazolo[4,5-B]Pyridine-7-Carboxylic Acid
CAS No.	852388-72-8
Molecular Formula	C20H18ClN3O2S
Molecular Weight	399.89 g/mol
Synonyms	5-(3-Chlorophenyl)-2-(1-piperidinyl)[1,3]thiazolo[4,5-b]pyridine-7-carboxylic acid; 852388-72-8; Thiazolopyridine-7-carboxylic acid derivative; 2-Piperidin-1-yl-5-(3-chlorophenyl)thiazolo[4,5-b]pyridine-7-carboxylic acid; 7-Carboxy-5-(3-chlorophenyl)-2-(piperidin-1-yl)thiazolo[4,5-b]pyridine; [1,3]Thiazolo[4,5-b]pyridine-7-carboxylic acid, 5-(3-chlorophenyl)-2-(1-piperidinyl)-
EINECS	Contact for details

Quality Control

Our 5-(3-Chlorophenyl)-2-Piperidin-1-Yl[1,3]Thiazolo[4,5-B]Pyridine-7-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided for each lot, detailing results from HPLC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.