Description

2,7-Diazaspiro[4.5]Decan-1-One, 2-Phenyl-, (Hydrochloride) (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders. Researchers and process chemists in the pharmaceutical and biotechnology industries require this material for its potential in developing new therapeutic agents with improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A critical building block for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for novel drug discovery.
• CNS Drug Development: Particularly relevant in the synthesis of potential therapeutics for neurological and psychiatric conditions.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study biological pathways and target validation.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development pipelines.

Basic Information

Product Name	2,7-Diazaspiro[4.5]Decan-1-One, 2-Phenyl-, (Hydrochloride) (1:1)
CAS No.	852338-81-9
Molecular Formula	C14H19N2O·HCl
Molecular Weight	266.78 g/mol (Free base: 231.32 g/mol)
Synonyms	2-Phenyl-2,7-diazaspiro[4.5]decan-1-one hydrochloride; 2-Phenyl-1-oxa-2,7-diazaspiro[4.5]decane hydrochloride; 2-Phenyl-2,7-diazaspiro[4.5]decan-1-one HCl; 852338-81-9; Spirocyclic diaza compound hydrochloride; 1-Oxa-2,7-diazaspiro[4.5]decane, 2-phenyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our production of 2,7-Diazaspiro[4.5]Decan-1-One, 2-Phenyl-, (Hydrochloride) (1:1) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	98.0 - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.