Description

2,5-Dibromopyridine-3-Boronic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound is specifically engineered to enable the rapid construction of complex molecular architectures through key cross-coupling reactions. It is a critical raw material for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials science sectors, where precision and reliability are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functional group makes it an ideal partner for palladium-catalyzed coupling reactions to form biaryl and heterobiaryl structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and tags.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Product Name	2,5-Dibromopyridine-3-Boronic Acid
CAS No.	852228-14-9
Molecular Formula	C5H4BBr2NO2
Molecular Weight	280.71 g/mol
Synonyms	(2,5-Dibromopyridin-3-yl)boronic Acid; 3-Borono-2,5-dibromopyridine; 2,5-Dibromo-3-pyridineboronic Acid; 2,5-Dibromo-3-pyridinylboronic Acid; 2,5-Dibromo-3-boronopyridine; 852228-14-9; 3-Pyridineboronic acid, 2,5-dibromo-
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dibromopyridine-3-Boronic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and IR spectroscopy, is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.