Description

2,5-Dibromonicotinaldehyde is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional aldehyde and halogenated pyridine structure makes it a valuable precursor for constructing complex heterocyclic systems and pharmaceutical intermediates. This high-purity compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the bromine substituents.

Basic Information

Product Name	2,5-Dibromonicotinaldehyde
CAS No.	852181-11-4
Molecular Formula	C6H3Br2NO
Molecular Weight	264.90 g/mol
Synonyms	2,5-Dibromo-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 2,5-dibromo-; 2,5-Dibromopyridine-3-carbaldehyde; Nicotinaldehyde, 2,5-dibromo-; 2,5-Dibromo-3-formylpyridine; 2,5-Dibromonicotinaldehyde; 852181-11-4
EINECS	Contact for details

Quality Control

Our 2,5-Dibromonicotinaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.