Description

Methyl 6-(1H-Pyrrol-1-Yl)Nicotinate is a high-purity, functionalized nicotinate derivative serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides requiring specific heterocyclic motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic and Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratory settings.
• Scale-up Process Chemistry: Used in optimizing synthetic routes from milligram to kilogram scale for pre-clinical and early-phase clinical material production.

Basic Information

Item	Detail
Product Name	Methyl 6-(1H-Pyrrol-1-Yl)Nicotinate
CAS No.	852180-80-4
Molecular Formula	C12H12N2O2
Molecular Weight	216.24 g/mol
Synonyms	Methyl 6-(1H-pyrrol-1-yl)pyridine-3-carboxylate; 6-(1H-Pyrrol-1-yl)nicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-(1H-pyrrol-1-yl)-, methyl ester; Methyl 6-pyrrol-1-ylnicotinate; 852180-80-4; Methyl 6-(pyrrol-1-yl)nicotinate
EINECS	Contact for details

Quality Control

Our Methyl 6-(1H-Pyrrol-1-Yl)Nicotinate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC/MS for solvent residue analysis, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.