Description

2-Amino-3-Fluoro-5-(Trifluoromethyl)Pyridine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and trifluoromethyl substituents on a fluoropyridine core, makes it indispensable for introducing specific physicochemical properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty chemicals, ligands for catalysis, and advanced materials requiring specific electronic properties.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-Amino-3-Fluoro-5-(Trifluoromethyl)Pyridine
CAS No.	852062-17-0
Molecular Formula	C6H4F4N2
Molecular Weight	180.10 g/mol
Synonyms	3-Fluoro-5-(trifluoromethyl)pyridin-2-amine; 2-Amino-3-fluoro-5-trifluoromethylpyridine; 5-(Trifluoromethyl)-3-fluoropyridin-2-amine; 3-Fluoro-5-trifluoromethyl-2-pyridinamine; 2-Pyridinamine, 3-fluoro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated pyridine intermediates. Production follows cGMP guidelines where applicable, and each batch is accompanied by a comprehensive Certificate of Analysis (COA). Our standard quality commitment includes verification of identity, purity, and impurity profiles to ensure reliable performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.