Description

3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carboxamide is a high-value, multi-fluorinated pyridine derivative serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence profiles.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science: Potential building block for the synthesis of fluorinated polymers, liquid crystals, and electronic materials requiring specific dielectric properties.
• Chemical Biology Probe: Employed in the design of molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carboxamide
CAS No.	852062-16-9
Molecular Formula	C7H4F4N2O
Molecular Weight	208.11 g/mol
Synonyms	2-Pyridinecarboxamide, 3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-5-trifluoromethylpicolinamide; 3-Fluoro-5-(trifluoromethyl)picolinamide; 3-Fluoro-5-(trifluoromethyl)-2-pyridinecarboxamide; 852062-16-9; Amidine, 3-fluoro-5-(trifluoromethyl)-2-pyridyl; Picolinamide, 3-fluoro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-(Trifluoromethyl)Pyridine-2-Carboxamide is manufactured under a cGMP-compliant quality management system and undergoes rigorous analytical testing. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to ensure compliance with your stringent R&D and scale-up requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.