Description

(S)-2-Amino-3-(2-Naphthyl)Propionicacidethylester CAS NO 851901-18-3 is a high-purity, non-natural amino acid derivative characterized by its chiral (S)-configuration and naphthyl side chain. This compound is a critical chiral building block for the synthesis of complex molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and advanced materials.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptide Synthesis: Serves as a protected amino acid ester for solid-phase and solution-phase peptide synthesis, enabling the incorporation of a bulky, hydrophobic naphthyl group.
• Chemical Biology Probes: Used in the design and synthesis of fluorescent probes, enzyme substrates, and inhibitors to study protein-protein interactions and enzymatic activity.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral test substrate in the development of new asymmetric synthetic methodologies.
• Material Science: Potential monomer for creating specialized polymers with unique optical or structural properties derived from the naphthalene moiety.

Basic Information

Item	Details
Product Name	(S)-2-Amino-3-(2-Naphthyl)Propionicacidethylester
CAS No.	851901-18-3
Molecular Formula	C₁₆H₁₇NO₂
Molecular Weight	255.31 g/mol
Synonyms	(S)-2-Amino-3-(naphthalen-2-yl)propanoic acid ethyl ester; L-2-Naphthylalanine ethyl ester; Ethyl (S)-2-amino-3-(naphthalen-2-yl)propanoate; (S)-Ethyl 2-amino-3-(2-naphthyl)propionate; 2-Naphthyl-L-alanine ethyl ester; (S)-3-(2-Naphthyl)alanine ethyl ester; (S)-2-Naphthylalanine ethyl ester; Ethyl L-2-naphthylalaninate
EINECS	Contact for details

Quality Control

Every batch of (S)-2-Amino-3-(2-Naphthyl)Propionicacidethylester is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and chiral integrity, meeting the stringent requirements of research and pre-clinical development. A detailed Certificate of Analysis (COA) including chiral purity (enantiomeric excess) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.