Description

(Rs)-4-(6-Methylpyridin-2-Yl)But-3-Yn-2-Ol is a chiral alkyne derivative featuring a pyridine moiety, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its ability to act as a key building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, structurally defined intermediates for asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyridine and alkyne functionalities contribute to biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic electronic materials and polymers due to its conjugated alkyne system.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including click chemistry and cross-coupling reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance and flavor molecules.

Basic Information

Product Name	(Rs)-4-(6-Methylpyridin-2-Yl)But-3-Yn-2-Ol
CAS No.	851854-84-7
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	(R)-4-(6-Methyl-2-pyridinyl)-3-butyn-2-ol; (R)-4-(6-Methylpyridin-2-yl)but-3-yn-2-ol; 4-(6-Methyl-2-pyridinyl)-3-butyn-2-ol, (R)-; (R)-4-(6-Methyl-2-pyridyl)but-3-yn-2-ol; (R)-1-(6-Methylpyridin-2-yl)-3-butyn-2-ol; (R)-4-(6-Methyl-2-pyridinyl)-2-butyn-4-ol; (R)-4-(6-Methylpyridin-2-yl)but-3-yn-2-ol (enantiomer); 851854-84-7
EINECS	Contact for details

Quality Control

Our (Rs)-4-(6-Methylpyridin-2-Yl)But-3-Yn-2-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment. We adhere to cGMP principles where applicable to ensure supply chain integrity and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept tightly sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.