Description

2-(2-Bromo-Pyridin-3-Yl)-2,3-Dihydro-Benzofuran-5-Carboxylic Acid Metyl Ester CAS NO 851777-29-2 is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of novel pesticides or herbicides, leveraging its fused benzofuran-pyridine core.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-(2-Bromo-Pyridin-3-Yl)-2,3-Dihydro-Benzofuran-5-Carboxylic Acid Metyl Ester
CAS No.	851777-29-2
Molecular Formula	C16H13BrNO3
Molecular Weight	347.19 g/mol
Synonyms	2-(2-Bromopyridin-3-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid methyl ester; Methyl 2-(2-bromopyridin-3-yl)-2,3-dihydrobenzofuran-5-carboxylate; 2,3-Dihydro-2-(2-bromo-3-pyridinyl)-5-benzofurancarboxylic acid methyl ester; 851777-29-2; 2-(2-Bromo-3-pyridyl)-2,3-dihydrobenzofuran-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromo-Pyridin-3-Yl)-2,3-Dihydro-Benzofuran-5-Carboxylic Acid Metyl Ester is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and MS are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.